E-ISSN 2146-8133
 

Original Research (Original Article) 


Melatonin decreases eye pressure in depressive patients with normal intraocular pressure

Gokhan Ozdemir, Ebru Findikli.

Abstract
Background/Aim: In this study, we aimed to show the effect of melatonin, a pineal hormone, on intraocular pressure in patients with depression and normal ocular tension.
Methods: Twenty depressive patients for whose agomelatine, a melatonin drug, was deemed necessary for treatment of the primary disease were enrolled in the study. Ocular pressures at baseline, second and fourth-week visits were recorded using a Tono-Pen and a Goldmann applanation tonometer.
Results: Our study revealed that oral agomelatine therapy reduced intraocular pressure in the normotensive patients. The baseline intraocular pressure was 12.6±2.8 mm Hg with the Tono-Pen and 14.8 mm Hg with applanation tonometry. At the fourth week visit, the pressure measured with Tono-Pen was 11.5±2.9 mm-Hg and the pressure measured with applanation tonometer was 13.5±2.8 mm-Hg (p<0.05 for both measurements). There was a pressure decline of 9% compared to
the baseline.
Conclusion: Agomelatine is able to lower intraocular pressure in normotensive patients.

Key words: Agomelatine, melatonin, intraocular pressure, depression


 
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How to Cite this Article
Pubmed Style

Ozdemir G, Findikli E. Melatonin decreases eye pressure in depressive patients with normal intraocular pressure. Arch Clin Exp Surg. 2019; 8(1): 28-32. doi:10.5455/aces.20180720071622


Web Style

Ozdemir G, Findikli E. Melatonin decreases eye pressure in depressive patients with normal intraocular pressure. http://www.ejmaces.com/?mno=1471 [Access: March 28, 2020]. doi:10.5455/aces.20180720071622


AMA (American Medical Association) Style

Ozdemir G, Findikli E. Melatonin decreases eye pressure in depressive patients with normal intraocular pressure. Arch Clin Exp Surg. 2019; 8(1): 28-32. doi:10.5455/aces.20180720071622



Vancouver/ICMJE Style

Ozdemir G, Findikli E. Melatonin decreases eye pressure in depressive patients with normal intraocular pressure. Arch Clin Exp Surg. (2019), [cited March 28, 2020]; 8(1): 28-32. doi:10.5455/aces.20180720071622



Harvard Style

Ozdemir, G. & Findikli, . E. (2019) Melatonin decreases eye pressure in depressive patients with normal intraocular pressure. Arch Clin Exp Surg, 8 (1), 28-32. doi:10.5455/aces.20180720071622



Turabian Style

Ozdemir, Gokhan, and Ebru Findikli. 2019. Melatonin decreases eye pressure in depressive patients with normal intraocular pressure. Archives of Clinical and Experimental Surgery (ACES), 8 (1), 28-32. doi:10.5455/aces.20180720071622



Chicago Style

Ozdemir, Gokhan, and Ebru Findikli. "Melatonin decreases eye pressure in depressive patients with normal intraocular pressure." Archives of Clinical and Experimental Surgery (ACES) 8 (2019), 28-32. doi:10.5455/aces.20180720071622



MLA (The Modern Language Association) Style

Ozdemir, Gokhan, and Ebru Findikli. "Melatonin decreases eye pressure in depressive patients with normal intraocular pressure." Archives of Clinical and Experimental Surgery (ACES) 8.1 (2019), 28-32. Print. doi:10.5455/aces.20180720071622



APA (American Psychological Association) Style

Ozdemir, G. & Findikli, . E. (2019) Melatonin decreases eye pressure in depressive patients with normal intraocular pressure. Archives of Clinical and Experimental Surgery (ACES), 8 (1), 28-32. doi:10.5455/aces.20180720071622





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