Sarvagya Jain
Department of Surgery, Maharaja Yeshwant Rao Hospital and Mahatma Gandhi Memorial Medical College, Madhya Pradesh, IndiaPublications
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Research
A Randomized Control Study to Compare the Efficacy of Centchroman with Danazol in Control of Mastalgia in Fibrocystic Diseases of Breast
Author(s): Kelam Lavanya*, Sumit Shukla, Ankur Maheshwari, Avinash Goutam and Sarvagya Jain
Background: Mastalgia is the most common presenting symptom alongside lump and nodularity. There are several treatments in practice for treatment of mastalgia including the use of topical diclofenac ointment, oral linoleic acid (Mecgla), Vitamin E and topical evening primrose oil application. Danazol, an androgenic compound, has proved to be efficacious in the treatment of mastalgia, albeit with a range of side effects. Centchroman (or Ormiloxifene), sold under the trade name of Saheli, Chhaya and Sevista is a Selective Estrogen Receptor Modulator (SERM) has shown to be efficacious in treatment of mastalgia along with having fewer and milder side effects. This study aims at comparing the efficacy of Centchroman with that of Danazol in treatment of mastalgia due to fibrocystic diseases of breast and to assess the sustained response and recurr.. Read More»